ABSTRACT
High-quality sustainable development is the common goal pursued by all countries in the world. China's high-quality development (HQD) includes five concepts of "innovation, coordination, green, opening-up, and sharing ". In this context, we established an evaluation system that included these five fundamental characteristics, used the comprehensive entropy method and BP neural network to evaluate and predict the high-quality development of Hubei Province in China, and conducted a spatiotemporal deductive analysis. The study found that: 1) Economic growth still has an important impact on HQD, for all the five main indicators, "opening-up " and "innovation " have the highest impact weights, which are 0.379 and 0.278, respectively, while the proportions of coordination and sharing are both less than 0.1. 2) There are huge differences in the level of high-quality development between regions in Hubei Province. From 2010 to 2020, the average comprehensive index of Wuhan City was greater than 0.5, which is 7 times that of the second Xiangyang City, and 46 times that of the last Shennongjia district. 3) In the past few years, the overall high-quality development of Hubei Province has shown a fluctuating upward trend. However, due to the impact of COVID-19, during the following years, its comprehensive development index will decline by an average of 5% annually, but starting from 2022, it will gradually increase. As a result, tailored and coordinated sustainable environmental policies of integrating institutional and open-market measures should be provided.
ABSTRACT
Since the outbreak of coronavirus disease 2019 (COVID-19), more than 130,000 people worldwide have been infected. Many studies show that the testis is one of the organs with a high expression of angiotensin-converting enzyme 2 (ACE2), the receptor/binding protein of SARS-CoV-2, which has aroused public concerns about the possible damage to male fertility. This article presents a review and analysis of the existing literature, aiming to achieve an objective understanding of the significance of the ACE2 expression in the testis. Hitherto, clinical and laboratory data available on COVID-19 are not sufficient to provide any direct evidence that the testis is a target organ of the virus. Whether the coronavirus damages fertility in male patients with COVID-19 requires further investigation. In the absence of sufficient research-based evidence, damage of the virus to male fertility should not be over-interpreted.